James P. Allison, Ph.D.

The Nobel Prize in Physiology or Medicine 2018
Nobel co-recipient Tasuku Honjo

Cancer Immunologist. Discovered cancer therapy by inhibition of negative immune regulation. Pioneer. Place breaks/check points on inhibitory immune cells to attack cancer cells - curative. Interest: How T cells work. First Nobel Prize for cancer therapy. Family history of cancer. Modest.

"Motivation of scientists: to know what nobody else knows."

Thought Process

Discovered cancer therapy by inhibition of negative immune regulation.

Good to use the body's own tissues to fight disease.

Learning Point: In any situation, use locally available resources!