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Robert B. Woodward Ph.D.

Robert B. Woodward Ph.D.

The Nobel Prize in Chemistry 1965
National Medal of Science - Physical Sciences 1964

Award: "for his outstanding achievements in the art of organic synthesis"

Patents

Publication:1/79
Publication No:US 4692442 A
Title:6-substituted penem compounds
Publication Type:Grant
Publication Date:Sep 8, 1987
Filing Date:Nov 18, 1980
Inventors:Jacques Gosteli, Ivan Ernest, Marc Lang, Robert B. Woodward
Original Assignee:Ciba-Geigy Corporation
Abstract:The invention relates to 2-penem-3-carboxylic acid compounds of the formula ##STR1## in which Ra represents an organic radical bonded by a carbon atom to the ring carbon atom, a free, etherified or esterified hydroxy or mercapto group or a halogen atom, R1 represents hydrogen, an organic radical bonded by a carbon atom to the ring carbon atom, or an etherified mercapto group, and R2 represents a hydroxy group or an R2 A radical that together with the carbonyl grouping --C(═O)-- forms a protected carboxyl group, and to salts of such compounds with salt-forming groups, processes for the manufacture of such compounds, pharmaceutical preparations containing compounds of the formula I with pharmacological properties, and their use. The compounds have antibiotic activity.
Representative Figure:No Figure
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Publication:2/79
Publication No:US 4579684 A
Title:Process for the manufacture of enol derivatives
Publication Type:Grant
Publication Date:Aug 19, 1985
Filing Date:Feb 20, 1975
Inventors:Robert B. Woodward, Hans Bickel
Original Assignee:Ciba-Geigy Corporation
Abstract:The invention concerns a process for the manufacture of 7 beta -amino-3-cephem-3-ol-4-carboxylic acid compounds by ring closure of esters of2-[4-(substituted-thio)-3-acylamino-2-xoazetidin-1-yl]-3-substituted-amino-crotonic acids and solvolysing the enamino group in the resulting 7 beta -acylamino-3-substituted-amino-cephem-4-carboxylic acid esters.
Representative Figure:No Figure
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Publication:3/79
Publication No:US 4500457 A
Title:Process for preparing thia-aza compounds with a beta-lactam ring
Publication Type:Grant
Publication Date:Feb 19, 1985
Filing Date:Mar 1, 1982
Inventors:Jacques Gosteli, Ivan Ernest, Robert B. Woodward
Original Assignee:Ciba-Geigy Corporation
Abstract:2-Penem-3-carboxylic acid compounds of the formula (I) in which R1 represents hydrogen, an organic radical bonded by a carbon atom to the ring carbon atom or an etherified mercapto group and R2 represents hydroxy or a radical R2A forming together with the carbonyl grouping -C(=O)- a protected carboxyl group, 1-oxides thereof, as well as salts of such compounds having salt-forming groups, in racemic and optically active form, processes for their preparation, pharmaceutical compositions containing such compounds, and their use as antibiotics, and intermediates and their processes which are useful in the production of the compounds of the formula I.
Representative Figure:No Figure
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Publication:4/79
Publication No:US 4434287 A
Title:Process for the manufacture of enol derivatives
Publication Type:Grant
Publication Date:Oct 29, 1985
Filing Date:Sep 30, 1982
Inventors:Robert E. Woodward, Hans Bickel
Original Assignee:Ciba-Geigy Corporation
Abstract:The invention concerns a process for the manufacture of 7 beta -amino-3-cephem-3-ol-4-carboxylic acid compounds by ring closure of esters of 2-[4-(substituted-thio)-3-acylamino-2-oxoazetidin-1-yl]-3-substituted- amino-crotonic acids and solvolyzing the enamino group in the resulting 7 beta -acylamino-3-substituted-amino-cephem-4-carboxylic acid esters.
Representative Figure:No Figure
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Publication:5/79
Publication No:US 4364865 A
Title:Bicyclic unsaturated thia-aza compounds and 4-acylthio azetidinone intermediates
Publication Type:Grant
Publication Date:Dec 21, 1982
Filing Date:Jun 11, 1980
Inventors:Ivan Ernest, Jacques Gosteli, Robert B. Woodward
Original Assignee:Ciba-Geigy Corporation
Abstract:The invention relates to 6-amino-2-penem-3-carboxylic acid compounds of the formula ##STR1## in which R1 a denotes hydrogen or an amino protective group R1 A and R1 b represents hydrogen or an acyl radical Ac, or in which R1 a and R1 b conjointly form a bivalent amino protective group, R2 denotes hydroxyl or a radical R2 A which, together with the carbonyl grouping --C(═O)--, forms a protected carboxyl group, and R3 represents hydrogen or an organic radical which is linked via a carbon atom to the ring carbon atom, and 1-oxides thereof, as well as salts of such compounds having salt-forming groups, which compounds possess antibiotic properties, processes for the manufacture of such compounds, and also pharmaceutical formulations containing compounds of the formula I with pharmacological properties, and the use thereof, either as antibiotics, preferably in the form of pharmaceutical formulations, or as intermediate products.
Representative Figure:No Figure
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Publication:6/79
Publication No:US 4331676 A
Title:Thia-aza compounds with a β-lactam ring
Publication Type:Grant
Publication Date:May 25, 1982
Filing Date:May 4, 1978
Inventors:Jacques Gosteli, Ivan Ernest, Robert B. Woodward
Original Assignee:Ciba-Geigy Corporation
Abstract:2-Penem-3-carboxylic acid compounds of the formula ##STR1## in which R1 represents hydrogen, an organic radical bonded by a carbon atom to the ring carbon atom or an etherified mercapto group and R2 represents hydroxy or a radical R2 A forming together with the carbonyl grouping --C(═O)-- a protected carboxyl group, 1-oxides thereof, as well as salts of such compounds having salt-forming groups, in racemic and optically active form, processes for their preparation, pharmaceutical compositions containing such compounds, and their use as antibiotics, and intermediates and their processes which are useful in the production of the compounds of the formula I.
Representative Figure:No Figure
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Publication:7/79
Publication No:US 4301278 A
Title:Process for the manufacture of enol derivatives
Publication Type:Grant
Publication Date:Nov 17, 1981
Filing Date:Mar 26, 1979
Inventors:Robert B. Woodward, Hans Bickel
Original Assignee:Ciba-Geigy Corporation
Abstract:7β-Amino-3-cephem-3-cl-4-carboxylic-acid compounds of the formula ##STR1## wherein R1 a represents hydrogen or an amino protective group R1 A and R1 b represents hydrogen or an acyl group Ac, or R1 a and R1 b together represent a bivalent amino protective group, R2 represents hydroxyl or a radical R2 A which together with the carbonyl grouping --C(═O)-- forms a protected carboxyl group and R3 represents hydrogen, lower alkyl or a hydroxyl protective group, and 1-oxides of 3-cephem compounds of the formula IA, and the corresponding 2-cephem compounds are prepared in that a compound of the formula ##STR2## wherein R1 a, R1 b and R2 A have the meanings mentioned under formula IA, R3 o represents lower alkyl or a hydroxyl protective group and Y represents a group which is removed, is treated with a base; also comprised are intermediate products.
Representative Figure:No Figure
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Publication:8/79
Publication No:US 4256739 A
Title:7β-Amino-3-thio-3-cephem-4-carboxylic acid compounds, and antibacterial compositions and methods using them
Publication Type:Grant
Publication Date:Mar 17, 1981
Filing Date:Aug 26, 1975
Inventors:Robert B. Woodward, Hans Bickel
Original Assignee:Robert B. Woodward, Hans Bickel
Abstract:7β-Amino-3-R3 -thio-3-cephem-4-carboxylic acid compounds of the formula ##STR1## wherein R1 a represents hydrogen or an amino protective group R1 A and R1 b represents hydrogen or an acyl group Ac, or R1 a and R1 b conjointly represent a divalent amino protective group, R2 represents hydroxyl or a radical R2 A which, conjointly with the carbonyl grouping --C(═O)--, forms a protected carboxyl group and R3 represents an unsubstituted or substituted hydrocarbon radical or an unsubstituted or substituted heterocyclic radical, and salts of such compounds with salt-forming groups possess antibiotic properties.
Representative Figure:No Figure
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Publication:9/79
Publication No:US 4255328 A
Title:Sulfide intermediates for the manufacture of enol derivatives
Publication Type:Grant
Publication Date:Mar 10, 1981
Filing Date:Nov 20, 1978
Inventors:Nov 20, 1978
Original Assignee:Ciba-Geigy Corporation
Abstract:7β-amino-3-cephem-3-ol-4-carboxylic-acid compounds of the formula ##STR1## wherein R1 a represents hydrogen or an amino protective group R1 A and R1 b represents hydrogen or an acyl group Ac, or R1 a and R1 b together represent a bivalent amino protective group, R2 represents hydroxyl or a radical R2 A which together with the carbonyl grouping --C(═O)-- forms a protected carboxyl group and R3 represents hydrogen, lower alkyl or a hydroxyl protective group, and 1-oxides of 3-cephem compounds of the formula IA, and the corresponding 2-cephem compounds are prepared in that a compound of the formula ##STR2## wherein R1 a, R1 b and R2 A have the meanings mentioned under formula IA, R3 o represents lower alkyl or a hydroxyl protective group and Y represents a group which is removed, is treated with a base; also comprised are intermediate products.
Representative Figure:No Figure
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Publication:10/79
Publication No:US 4161476 A
Title:α-Halo-2-oxo-1-azetidinemethane-carboxylic acid compounds
Publication Type:Grant
Publication Date:Jul 17, 1979
Filing Date:Jul 11, 1977
Inventors:Karl Heusler, Robert B. Woodward
Original Assignee:Karl Heusler, Robert B. Woodward
Abstract:α-Hydroxy-2-oxo-1-azetidinemethane-carboxylic acid compounds of formula ##STR1## wherein R1 represents a hydrogen atom or the organic residue of an alcohol, R2 represents a hydrogen atom or an acyl residue, R3 represents an organic residue and R4 represents a hydrogen atom, when R2 stands for an acyl residue, or the two groups R3 and R4 together represent a disubstituted carbon atom, when R2 stands for a hydrogen atom or an acyl group, are useful as intermediates for the manufacture of pharmacologically active compounds.
Representative Figure:No Figure
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Publication:11/79
Publication No:US 4147864 A
Title:Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds
Publication Type:Grant
Publication Date:Apr 3, 1979
Filing Date:Dec 2, 1976
Inventors:Robert B. Woodward, Hans Bickel
Original Assignee:Ciba-Geigy Corporation
Abstract:7β-amino-3-cephem-3-ol-4-carboxylic-acid compounds of the formula ##STR1## wherein R1 a represents hydrogen or an amino protective group R1 A and R1 Brepresents hydrogen or an acyl group Ac, or R1 a and R1 b together represent abivalent amino protective group, R2 represents hydroxyl or a radical R2 A which together with the carbonyl grouping --C(═O)-- forms a protected carboxyl group and R3 represents hydrogen, lower alkyl or a hydroxyl protective group, and 1-oxides or 3-cephem compounds of the formula IA, and the corresponding 2-cephem compounds are prepared in that a compound of the formula ##STR2## wherein R1a, R1 b and R2 A have the meanings mentioned under formula IA, R3 o represents lower alkyl or a hydroxyl protective group and Y represents a group which is removed, is treated with a base; also comprised are intermediate products.
Representative Figure:No Figure
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Publication:12/79
Publication No:US 4110533 A
Title:Process for the manufacture of enol derivatives
Publication Type:Grant
Publication Date:Aug 29, 1978
Filing Date:Feb 10, 1976
Inventors:Robert B. Woodward, Hans Bickel
Original Assignee:Ciba-Geigy Corporation
Abstract:The invention concerns a process for the manufacture of 7β-amino-3-cephem-3-ol-4-carboxylic acid compounds by ring closure of esters of 2-[4-(substituted-thio)-3-acylamino-2-oxoazetidin-1-yl]-3-substituted-amino-crotonic acids and solvolysing the enamino group in the resulting 7β-acylamino-3-substituted-amino-cephem-4-carboxylic acid esters.
Representative Figure:No Figure
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Publication:13/79
Publication No:US 4070477 A
Title:2-Penem compounds
Publication Type:Grant
Publication Date:Jan 24, 1978
Filing Date:Dec 2, 1976
Inventors:Ivan Ernest, Jacques Gosteli, Robert Burns Woodward
Original Assignee:Ciba-Geigy Corporation
Abstract:The invention relates to 6-amino-2-penem-3-carboxylic acid compounds of the formula ##STR1## in which R1 a denotes hydrogen or an amino protective group R1 A and R1 b represents hydrogen or an acyl radical Ac, or in which R1 a and R1 b conjointly form a bivalent amino protective group, R2 denotes hydroxyl or aradical R2 A which, together with the carbonyl grouping --C(═0)--, forms aprotected carboxyl group, and R3 represents hydrogen or an organic radical which is linked via a carbon atom to the ring carbon atom, and 1-oxides thereof, as well as salts of such compounds having salt-forming groups, which compounds possess antibiotic properties, processes for the manufacture of such compounds, and also pharmaceutical formulations containing compounds of the formula I with pharmacological properties, and the use thereof, either as antibiotics, preferably in the form of pharmaceutical formulations, or as intermediate products.
Representative Figure:No Figure
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Publication:14/79
Publication No:US 4052408 A
Title:Oxyacetic acid compounds and process for their manufacture
Publication Type:Grant
Publication Date:Oct 4, 1977
Filing Date:Nov 18, 1974
Inventors:Karl Heusler, Robert Burns Woodward
Original Assignee:Ciba-Geigy Corporation
Abstract:α-Hydroxy-2-oxo-1-azetidinemethane-carboxylic acid compounds of formula ##STR1## wherein R1 represents a hydrogen atom or the organic residue of an alcohol, R2 represents a hydrogen atom or an acyl residue, R3 represents an organic residue and R4 represents a hydrogen atom, when R2 stands for an acyl residue, or the two groups R3 and R4 together represent a disubstituted carbon atom, when R2 stands for a hydrogen atom or an acyl group, are useful as intermediates for the manufacture of pharmacologically active compounds.
Representative Figure:No Figure
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Publication:15/79
Publication No:US 3950362 A
Title:Oxabicyclooctanes and process for their manufacture
Publication Type:Grant
Publication Date:Apr 13, 1976
Filing Date:Feb 2, 1973
Inventors:Woodward, Robert B.
Original Assignee:Ciba-Geigy Corporation
Abstract:Compounds of the formula ##SPC1## Wherein Z4 and Z5 each independently represent free, etherified or esterified hydroxy groups, are produced by diazotisation of 2-exo-amino-3,4-endo-dihydroxy-8-Z4 -7-oxabicyclo [4,3,0]nonane followed by ring contraction, they are intermediates in the synthesis of prostaglandins.
Representative Figure:No Figure
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Publication:16/79
Publication No:US 3941813 A
Title:Dioxatricyclodecanes and process for their manufacture
Publication Type:Grant
Publication Date:March 2, 1976
Filing Date:February 2, 1973
Inventors:Woodward, Robert B.
Original Assignee:Ciba-Geigy Corporation
Abstract:A compound of formula IS PRODUCED BY REACTING 4 alpha ,5 alpha -EPOXY-9,10-DIOXATRICYCLO[4,3,1,03,8]DECANE WITH AMMONIA OR A REACTION FUNCTIONAL DERIVATIVE THEREOF; IT IS AN INTERMEDIATE FOR THE SYNTHESIS OF PROSTAGLANDINS.
Representative Figure:No Figure
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Publication:17/79
Publication No:US 3919249 A
Title:Dioxatricyclodecanol, esters thereof, and process for their manufacture
Publication Type:Grant
Publication Date:Nov 11, 1975
Filing Date:Feb 2, 1973
Inventors:Robert Burns Woodward
Original Assignee:Ciba Geigy Corp
Abstract:Compounds of formula WHEREIN Z3 represents a free or esterified hydroxy group are prepared by cyclising an ester of 3-hydroxymethyl-2,4-dioxabicyclo[3,3,1 non-6-ene; they are intermediates for the synthesis of prostaglandins
Representative Figure:No Figure
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Publication:18/79
Publication No:US 3914258 A
Title:New oxabicyclononanes
Publication Type:Grant
Publication Date:Oct 21, 1975
Filing Date:Feb 2, 1973
Inventors:Robert Burns Woodward
Original Assignee:Ciba Geigy Corp
Abstract:Compounds of the formula WHEREIN Z4 represents a free, esterified or etherified hydroxy group, are produced by solvolysing 4 beta -amino-9,10-dioxatricyclo [4,3,1,03,8]decan-5 alpha -ol; they are intermediates in the synthesis of prostaglandins.
Representative Figure:No Figure
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Publication:19/79
Publication No:US 3901919 A
Title:Bicyclononane diol and esters
Publication Type:Grant
Publication Date:Aug 26, 1975
Filing Date:Feb 2, 1973
Inventors:Robert Burns Woodward
Original Assignee:Ciba Geigy Corp
Abstract:No Abstract
Representative Figure:No Figure
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Publication:20/79
Publication No:US 3900500 A
Title:Esters of hydroxymethyl-dioxabicyclononene
Publication Type:Grant
Publication Date:Aug 19, 1975
Filing Date:Feb 2, 1973
Inventors:Woodward, Robert B.
Original Assignee:Ciba Geigy Corp
Abstract:No Abstract
Representative Figure:No Figure
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Publication:21/79
Publication No:US 3898248 A
Title:Dioxatricyclodecenes
Publication Type:Grant
Publication Date:Aug 5, 1975
Filing Date:Feb 2, 1973
Inventors:Robert Burns Woodward
Original Assignee:Ciba Geigy Corp
Abstract:A compound of the formula IS PREPARED BY ELIMINATING THE ESTER GROUP FROM ONE ESTER OF 9,10-DIOXATRICYCLO[4,3,1,03,8]DECAN-4 beta -OL; IT IS AN INTERMEDIATE FOR THE SYNTHESIS OF PROSTAGLANDINS.
Representative Figure:No Figure
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Publication:22/79
Publication No:US 3880833 A
Title:Certain bis-(3-amino-2-oxo-1-azetidinyl)-disulfides
Publication Type:Grant
Publication Date:Apr 29, 1975
Filing Date:Oct 12, 1971
Inventors:Hans Bickel, Karl Heusler, Riccardo Scartazzini, Robert Burns Woodward
Original Assignee:Ciba Geigy Corp
Abstract:The invention concerns the manufacture of bis-(cis-3-amino-2-oxo-1-azetidinyl)-disulfides and corresponding N-protected derivatives thereof by oxidation of 4-thia-2,6-diaza-bicyclo[3.2.0]heptan-6-ones and, if desired, protection, e.g. acylation, of the amino group. The products are intermediates for the manufacture of 7-amino-ceph-3-em-4-carboxylic acid compounds with antibiotic properties.
Representative Figure:No Figure
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Publication:23/79
Publication No:US 3862225 A
Title:D-ring substituted tetracyclines
Publication Type:Grant
Publication Date:Jan 21, 1975
Filing Date:Jan 7, 1971
Inventors:Lloyd H Conover, Robert B Woodward
Original Assignee:Pfizer
Abstract:No Abstract
Representative Figure:No Figure
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Publication:24/79
Publication No:US 3835130 A
Title:2-thia-cepham and cephem-4-carboxylic acids
Publication Type:Grant
Publication Date:Sep 10, 1974
Filing Date:Oct 29, 1971
Inventors:Woodward, Robert B.
Original Assignee:Ciba Geigy Corp
Abstract:The invention concerns 7-amino-2-thiacepham-4-carboxylic acid and 7-amino-2-thiaceph-3-em-4-carboxylic acid compounds and their N-acyl derivatives. These compounds, particularly the latter ones have antibacterial properties. The invention also concerns process for the manufacture of such compounds and intermediates and starting materials useful in such process.
Representative Figure:No Figure
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Publication:25/79
Publication No:US 3719672 A
Title:4-substituted methylene-7-amino-8-oxo-5-thia-1-aza-bicyclo(4,2,0 oct-2-ene-2-carboxylic acids
Publication Type:Grant
Publication Date:Mar 6, 1973
Filing Date:Dec 2, 1969
Inventors:I Ernest, K Heusler, R Woodward
Original Assignee:Ciba Geigy Corp
Abstract:No Abstract
Representative Figure:No Figure
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Publication:26/79
Publication No:US 3716465 A
Title:Process for the manufacture of thiazacyclic hydroxy compounds
Publication Type:Grant
Publication Date:Feb 13, 1973
Filing Date:Nov 23, 1970
Inventors:K Heusler, R Woodward
Original Assignee:Ciba Geigy Corp
Abstract:No Abstract
Representative Figure:No Figure
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Publication:27/79
Publication No:US 3697552 A
Title:Anthracyclidine-acetic acid derivatives
Publication Type:Grant
Publication Date:Oct 10, 1972
Filing Date:Oct 31, 1969
Inventors:Lloyd H Conover, Robert B Woodward
Original Assignee:Pfizer
Abstract:No Abstract
Representative Figure:No Figure
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Publication:28/79
Publication No:US 3681370 A
Title:Certain acyloxy thiazolidines and process for their manufacture
Publication Type:Grant
Publication Date:Aug 1, 1972
Filing Date:Nov 24, 1969
Inventors:Woodward, Robert B.
Original Assignee:Woodward, Robert B.
Abstract:Process which comprises treating a saturated cyclic alpha -hydrazino-thioether, in which the hydrazino group is N,N'-disubstituted by esterified carboxyl groups, with an oxidation reagent capable of furnishing an acyloxy group; in a resulting saturated cyclic alpha -acyloxy-thioether the acyloxy group may be converted into the hydroxyl group. The products are useful in the synthesis of 7-amino-cephalosporanic acids.
Representative Figure:No Figure
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Publication:29/79
Publication No:US 3509184 A
Title:Anthracyclidine-acetic acid derivatives
Publication Type:Grant
Publication Date:Apr 28, 1970
Filing Date:Aug 1, 1966
Inventors:Lloyd H Conover, Robert B Woodward
Original Assignee:Pfizer & Co C
Abstract:No Abstract
Representative Figure:No Figure
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Publication:30/79
Publication No:US 3502697 A
Title:Antibacterial agents
Publication Type:Grant
Publication Date:Mar 24, 1970
Filing Date:Jan 3, 1967
Inventors:Woodward, Robert B.
Original Assignee:Pfizer & Co C
Abstract:No Abstract
Title:
Representative Figure:No Figure
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Publication:31/79
Publication No:US 3502660 A
Title:2-((5'-(3' and/or 4'-substituted)isoxazoyl) methylidene)-3,4,10-trioxo-1,2,3,4,4a,9,9a,10-octahydroanthracenes
Publication Type:Grant
Publication Date:Mar 24, 1970
Filing Date:Jan 12, 1967
Inventors:Kenneth Butler, Lloyd H Conover, Robert B Woodward
Original Assignee:Pfizer & Co C
Abstract:No Abstract
Representative Figure:No Figure
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Publication:32/79
Publication No:US 3498996 A
Title:Process for manufacture of 5-esterified hydroxy - thiazolidine - 4 - carboxylic acids
Publication Type:Grant
Publication Date:Mar 3, 1970
Filing Date:Jan 26, 1967
Inventors:Woodward, Robert B.
Original Assignee:Woodward, Robert B.
Abstract:No Abstract
Representative Figure:No Figure
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Publication:33/79
Publication No:US 3497532 A
Title:Antibacterial agents
Publication Type:Grant
Publication Date:Feb 24, 1970
Filing Date:Sep 2, 1966
Inventors:Woodward, Robert B.
Original Assignee:Pfizer & Co C
Abstract:No Abstract
Representative Figure:No Figure
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Publication:34/79
Publication No:US 3483216 A
Title:2,2-disubstituted 3-acyl-5-amino-thiazolidine-4-carboxylic acids
Publication Type:Grant
Publication Date:Dec 9, 1969
Filing Date:Aug 22, 1966
Inventors:Woodward, Robert B.
Original Assignee:Woodward, Robert B.
Abstract:No Abstract
Representative Figure:No Figure
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Publication:35/79
Publication No:US 3468933 A
Title:Hydroxymethane carboxylic acid esters and process for their manufacture
Publication Type:Grant
Publication Date:Sep 23, 1969
Filing Date:Aug 22, 1966
Inventors:Woodward, Robert B.
Original Assignee:Woodward, Robert B.
Abstract:No Abstract
Representative Figure:No Figure
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Publication:36/79
Publication No:US 3449336 A
Title:Process for preparing novel intermediates useful for preparing 7-amino-cephalosporanic acid and derivatives thereof
Publication Type:Grant
Publication Date:Jun 10, 1969
Filing Date:Aug 22, 1966
Inventors:Woodward, Robert B.
Original Assignee:Woodward, Robert B.
Abstract:No Abstract
Representative Figure:No Figure
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Publication:37/79
Publication No:US 3329670 A
Title:Arylazopyrazole lactone dyes
Publication Type:Grant
Publication Date:Jul 4, 1967
Filing Date:Feb 3, 1966
Inventors:Dershowitz Samuel, Robert B Woodward
Original Assignee:Polaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
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Publication:38/79
Publication No:US 3288778 A
Title:Azo and anthraquinone dye developers
Publication Type:Grant
Publication Date:Nov 29, 1966
Filing Date:Oct 5, 1964
Inventors:Blout Elkan R, Cohen Saul G, Rogers Howard G, Simon Myron S, Woodward Robert B
Original Assignee:Polaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
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Publication:39/79
Publication No:US 3252969 A
Title:p-dihydroxyphenyl sulfamyl azo and anthraquinone dyestuffs
Publication Type:Grant
Publication Date:May 24, 1966
Filing Date:Nov 7, 1962
Inventors:Blout Elkan R, Milton Green, Rogers Howard G, Woodward Robert B
Original Assignee:Polaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
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Publication:40/79
Publication No:US 3249643 A
Title:Tricyclo [5. 2. 1. 04, 10]-2, 5, 8-decatriene
Publication Type:Grant
Publication Date:May 3, 1966
Filing Date:Jan 7, 1964
Inventors:Woodward, Robert B.
Original Assignee:Woodward, Robert B.
Abstract:No Ahstract
Representative Figure:No Figure
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Publication:41/79
Publication No:US 3230085 A
Title:Photographic products, processes and compositions
Publication Type:Grant
Publication Date:Jan 18, 1966
Filing Date:Apr 6, 1961
Inventors:Samuel Dershowitz, Woodward Robert B
Original Assignee:Polaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
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Publication:42/79
Publication No:US 3209016 A
Title:Anthraquinone derivatives containing an ortho- or para-dihydroxyphenylalkylamino substituent
Publication Type:Grant
Publication Date:Sep 28, 1965
Filing Date:Oct 25, 1963
Inventors:Blout Elkan R, Cohler Marilyn R, Milton Green, Simon Myron S, Woodward Robert B
Original Assignee:Polaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
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Publication:43/79
Publication No:US 3188348 A
Title:12alpha-deoxytetracycline oxidation process
Publication Type:Grant
Publication Date:Jun 8, 1965
Filing Date:Jul 9, 1962
Inventors:Philip N Gordon, Butler Kenneth, Robert B Woodward
Original Assignee:Pfizer & Co C
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:44/79
Publication No:US 3135606 A
Title:Novel photographic products and processes employing anthraquinone dye
Publication Type:Grant
Publication Date:Jun 2, 1964
Filing Date:Oct 26, 1962
Inventors:Blout Elkan R, Cohler Marilyn R, Milton Green, Simon Myron S, Woodward Robert B
Original Assignee:Polaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:45/79
Publication No:US 3019107 A
Title:Novel photographic products, processes and compositions
Publication Type:Grant
Publication Date:Jan 30, 1962
Filing Date:Sep 25, 1956
Inventors:Elkan R Blout, Howard G Rogers, Myron S Simon, Robert B Woodward
Original Assignee:Polaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:46/79
Publication No:US 2883384 A
Title:Production of reserpine and analogs thereof
Publication Type:Grant
Publication Date:April 21, 1959
Filing Date:May 3, 1956
Inventors:Woodward, Robert B.
Original Assignee:Research Corp
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:47/79
Publication No:US 2857275 A
Title:Photographic compositions and processes
Publication Type:Grant
Publication Date:Oct 21, 1958
Filing Date:Nov 8, 1954
Inventors:Blout Elkan R, Cohen Saul G, Land Edwin H, Milton Green, Tracy Helen J, Woodward Robert B
Original Assignee:Polaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
Family
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Espacenet
Publication:48/79
Publication No:US 2857274 A
Title:Photographic compositions and processes
Publication Type:Grant
Publication Date:Oct 21, 19584
Filing Date:Sep 4, 1953
Inventors:Blout Elkan R, Cohen Saul G, Land Edwin H, Milton Green, Tracy Helen J, Woodward Robert B
Original Assignee:GPolaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:49/79
Publication No:US 2802873 A
Title:Production of steroid intermediate
Publication Type:Grant
Publication Date:Aug 13, 1957
Filing Date:Apr 13, 1951
Inventors:Woodward, Robert B.
Original Assignee:Research Corp
Abstract:No Abstract
Representative Figure:No Figure
Family
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Espacenet
Publication:50/79
Publication No:US 2745879 A
Title:Hexahydronaphthalenes and production thereof
Publication Type:Grant
Publication Date:May 15, 1956
Filing Date:May 19, 1953
Inventors:Woodward, Robert B.
Original Assignee:Research Corp
Abstract:No Abstract
Representative Figure:No Figure
Family
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Espacenet
Publication:51/79
Publication No:US 2702805 A
Title:Production of steroids
Publication Type:Grant
Publication Date:Feb 22, 1955
Filing Date:May 19, 1953
Inventors:Woodward, Robert B.
Original Assignee:Research Corp
Abstract:No Absract
Representative Figure:No Figure
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Espacenet
Publication:52/79
Publication No:US 2701807 A
Title:Steroid aldehydes and process
Publication Type:Grant
Publication Date:Feb 8, 1955
Filing Date:Jan 31, 1952
Inventors:Woodward, Robert B.
Original Assignee:Research Corp
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:53/79
Publication No:US 2687435 A
Title:1, 14-dimethyl-2-keto-6, 7-dihydroxy-2, 3, 4, 5, 6, 7, 8, 12, 13, 14-decahydrophenan-threne and process for preparing same
Publication Type:Grant
Publication Date:Aug 24, 1954
Filing Date:May 19, 1953
Inventors:Woodward, Robert B.
Original Assignee:Research Corp
Abstract:No Abstract
Representative Figure:No Figure
Family
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Espacenet
Publication:54/79
Publication No:US 2681366 A
Title:Production of 2-keto-10-methyl-1, 2, 5, 8, 9, 10-hexahydronaphthalene
Publication Type:Grant
Publication Date:Jun 15, 1954
Filing Date:Jan 31, 1952
Inventors:Woodward, Robert B.
Original Assignee:Research Corp
Abstract:No Abstract
Representative Figure:No Figure
Family
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Espacenet
Publication:55/79
Publication No:US 2675396 A
Title:Steroid aldehydes and process
Publication Type:Grant
Publication Date:Apr 13, 1954
Filing Date:May 19, 1953
Inventors:Woodward, Robert B.
Original Assignee:Woodward, Robert B.
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:56/79
Publication No:US 2674533 A
Title:Compositions and processes for the development of silver halide elements
Publication Type:Grant
Publication Date:Apr 6, 1954
Filing Date:Jul 10, 1952
Inventors:Woodward, Robert B.
Original Assignee:Polaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:57/79
Publication No:US 2672482 A
Title:AProduction of steroids
Publication Type:Grant
Publication Date:Mar 16, 1954
Filing Date:Jan 31, 1952
Inventors:Woodward, Robert B.
Original Assignee:Research Corp
Abstract:No Abstract
Representative Figure:No Figure
Family
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Espacenet
Publication:58/79
Publication No:US 2657972 A
Title:Copolymer of l-leucine and dl-phenylalanine
Publication Type:Grant
Publication Date:Nov 3, 1953
Filing Date:Sep 6, 1952
Inventors:Woodward, Robert B.
Original Assignee:Woodward, Robert B.
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:59/79
Publication No:US 2520673 A
Title:Acid salts of an n-acetyl-10-trimethylammoniumdihydrohomomeroquinene ethyl ester and their production
Publication Type:Grant
Publication Date:Aug 29, 1950
Filing Date:Mar 22, 1949
Inventors:Doering William Von Eggers, Robert B Woodward
Original Assignee:Polaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:60/79
Publication No:US 2494689 A
Title:Method and apparatus for producing twisted thermoplastic resin strips
Publication Type:Grant
Publication Date:Jan 17, 1950
Filing Date:Feb 25, 1947
Inventors:Robert W Canfield, Robert B Woodward
Original Assignee:Plax Corp
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:61/79
Publication No:US 2475932 A
Title:7-hydroxyisoquinoline derivatives and methods of preparing the same
Publication Type:Grant
Publication Date:Jul 12, 1949
Filing Date:Nov 4, 1943
Inventors:Doering William Von Eggers, Robert B Woodward
Original Assignee:Polaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:62/79
Publication No:US 2447831 A
Title:Evaporated and deposited birefringent film comprising aromatic compound, the molecules of which contain planar groupings
Publication Type:Grant
Publication Date:Aug 24, 1948
Filing Date:Mar 3, 1945
Inventors:Woodward, Robert B.
Original Assignee:Polaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:63/79
Publication No:US 2441019 A
Title:Light-polarizing suspension of oriented crystals of dibenzacridine periodide in cellulose acetate
Publication Type:Grant
Publication Date:May 4, 1948
Filing Date:Dec 16, 1943
Inventors:Jr William F Amon, Edwin H Land, Gofstein Raiph, Georgian Vlasios, Cutler D West, Robert B Woodward
Original Assignee:Polaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:64/79
Publication No:US 2395526 A
Title:Isoquinoline derivatives and methods of preparing the same
Publication Type:Grant
Publication Date:Feb 26, 1946
Filing Date:Feb 25, 1944
Inventors:Doering William Von Eggers, Robert B Woodward
Original Assignee:Polaroid Corp
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:65/79
Publication No:JP 01110668 A
Title:No Title
Publication Type:No Publication Type
Publication Date:No Publication Date
Filing Date:No Filing Date
Inventors:Woodward, Robert B.
Original Assignee:No Original Assignee
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:66/79
Publication No:CH 627759 A
Title:Process for preparing enol ether compounds
Publication Type:Grant
Publication Date:Jan 29, 1982
Filing Date:No Filing Date
Inventors:Woodward, Robert B., Bickel Hans
Original Assignee:Ciba-Geigy Corporation
Abstract:The invention provides a novel process for preparing O-substituted7beta-amino-3-cephem-3-ol-4-carboxylic acid compounds of the formula where R1 {a} is hydrogen or an amino-protective group R1{A}, R1 is hydrogen or an acyl group Ac, or R1{a} and R1 together are a bivalent amino-protective group, R2 is hydroxyl or a radical R2{A} which, together with the carbonyl group -C(=O)-, forms a protected carboxyl group, and R3 is lower alkyl or optionally substituted alpha -phenyl (lower alkyl), which comprises etherifying the 3-hydroxyl group in a 3-cephem-3-ol compound
Representative Figure:No Figure
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Espacenet
Publication:67/79
Publication No:CH 621337 A
Title:Process for the preparation of 3-aminocrotonylazetidinone derivatives
Publication Type:Grant
Publication Date:Jan 30, 1981
Filing Date:No Filing Date
Inventors:Woodward Robert Burns, Bickel Hans
Original Assignee:Ciba-Geigy Corporation
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:68/79
Publication No:CH 620444 A
Title:Process for the preparation of bicyclic unsaturated thiaaza compounds
Publication Type:Grant
Publication Date:Nov 28, 1980
Filing Date:No Filing Date
Inventors:Woodward, Robert B., Ernest Ivan
Original Assignee:Ciba-Geigy Corporation
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:69/79
Publication No:CH 619232 A
Title:Process for the preparation of substituted 3-cephem- or 2-cephem-3-mercapto-4-carboxylic acids
Publication Type:Grant
Publication Date:Sep 15, 1980
Filing Date:No Filing Date
Inventors:Woodward, Robert B., Bickel Hans
Original Assignee:Ciba-Geigy Corporation
Abstract:No Abstract
Title:
Representative Figure:No Figure
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Espacenet
Publication:70/79
Publication No:CH 614959 A
Title:Process for the preparation of 7-beta-aminocephem-3-01-4-carboxylic acid compounds
Publication Type:Grant
Publication Date:Dec 28, 1979
Filing Date:No Filing Date
Inventors:Woodward, Robert B.
Original Assignee:Ciba-Geigy Corporation
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:71/79
Publication No:CH 612422 A
Title:Process for the preparation of etherified 2-azetidinyl-3-hydroxycrotonic acid derivatives
Publication Type:Grant
Publication Date:Jul 31, 1979
Filing Date:No Filing Date
Inventors:Woodward, Robert B., Bickel Hans
Original Assignee:Ciba-Geigy Corporation
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:72/79
Publication No:CH 610584 A
Title:Process for the preparation of 2-(3-amino-2-oxo-4-sulphonylthio-1- azetidinyl)-3-methylenebutyric acid derivatives
Publication Type:Grant
Publication Date:Apr 30, 1979
Filing Date:No Filing Date
Inventors:Woodward, Robert B., Bickel Hans
Original Assignee:Ciba-Geigy Corporation
Abstract:No Abstract
Representative Figure:No Figure
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Espacenet
Publication:73/79
Publication No:CH 605999 A
Title:3-Thio-7-amino-3- and-2-cephem-4-carboxylic acids
Publication Type:Grant
Publication Date:Oct 13, 1978
Filing Date:No Filing Date
Inventors:Woodward, Robert B., Bickel Hans
Original Assignee:Ciba-Geigy Corporation
Abstract:No Abstract
Representative Figure:No Figure
Family
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Espacenet
Publication:74/79
Publication No:CH 605998 A
Title:3-Thio-7-amino-3- and-2-cephem-4-carboxylic acids
Publication Type:Grant
Publication Date:Oct 13, 1978
Filing Date:No Filing Date
Inventors:Woodward, Robert B., Bickel Hans
Original Assignee:Ciba-Geigy Corporation
Abstract:3-Thio-7-amino-3- and-2-cephem-4-carboxylic acids useful as broad-spectrum antibacterials and inters(NL-2.3.76)t
Representative Figure:No Figure
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Espacenet
Publication:75/79
Publication No:CH 605737 A
Title:7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn
Publication Type:Grant
Publication Date:Oct 13, 1978
Filing Date:DNo Filing Date
Inventors:Woodward, Robert B., Bickel Hans
Original Assignee:Ciba-Geigy Corporation
Abstract:7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn by cyclizing 3-alkoxy-2-(2-oxo-3-amino-4-thio-1-azetidinyl)-crotonic acid derives
Representative Figure:No Figure
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Espacenet
Publication:76/79
Publication No:CH 602635 A
Title:7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn
Publication Type:Grant
Publication Date:Jul 31, 1978
Filing Date:No Filing Date
Inventors:Woodward, Robert B., Bickel Hans
Original Assignee:Ciba-Geigy Corporation
Abstract:7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn by cyclizing 3-alkoxy-2-(2-oxo-3-amino-4-thio-1-azetidinyl)-crotonic acid derives
Representative Figure:No Figure
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Espacenet
Publication:77/79
Publication No:CH 602634 A
Title:7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn
Publication Type:Grant
Publication Date:Jul 31, 1978
Filing Date:No Filing Date
Inventors:Woodward, Robert B., Bickel Hans
Original Assignee:iba-Geigy Corporation
Abstract:7-Amino-3-hydroxy-2(or3)-cephem-4-carboxylic acid derivs prepn by cyclizing 3-alkoxy-2-(2-oxo-3-amino-4-thio-1-azetidinyl)-crotonic acid derivs
Representative Figure:No Figure
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Espacenet
Publication:78/79
Publication No:CH 601310 A
Title:7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn
Publication Type:Grant
Publication Date:Jul 14, 1978
Filing Date:No Filing Date
Inventors:Woodward, Robert B., Bickel Hans
Original Assignee:Ciba-Geigy Corporation
Abstract:7-Amino-3-hydroxy-2(or3)-cephem-4-carboxylic acid derivs prepn by cyclizing 3-alkoxy-2-(2-oxo-3-amino-4-thio-1-azetidinyl)-crotonic acid derivs
Representative Figure:No Figure
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Espacenet
Publication:79/79
Publication No:CH 601224 A
Title:7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn
Publication Type:Grant
Publication Date:Jun 30, 1978
Filing Date:No Filing Date
Inventors:Woodward, Robert B., Bickel Hans
Original Assignee:Ciba-Geigy Corporation
Abstract:7-Amino-3-hydroxy-2(or3)-cephem-4-carboxylic acid derivs prepn by cyclizing 3-alkoxy-2-(2-oxo-3-amino-4-thio-1-azetidinyl)-crotonic acid derivs
Representative Figure:No Figure
Family
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Espacenet

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Woodward
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Name: Robert Burns Woodward
Birth: 10 April 1917, Boston, MA, USA
Death: 8 July 1979, Cambridge, MA, USA
Institution: Harvard University, Cambridge, MA, USA
Award: "for his outstanding achievements in the art of organic synthesis"
Subject: natural products chemistry, organic chemistry
Portion of Cash: 1/1
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