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Robert B. Woodward Ph.D.
The Nobel Prize in Chemistry 1965
National Medal of Science - Physical Sciences 1964
Award: "for his outstanding achievements in the art of organic synthesis"
Patents
| Publication: | 1/79 |
| Publication No: | US 4692442 A |
| Title: | 6-substituted penem compounds |
| Publication Type: | Grant |
| Publication Date: | Sep 8, 1987 |
| Filing Date: | Nov 18, 1980 |
| Inventors: | Jacques Gosteli, Ivan Ernest, Marc Lang, Robert B. Woodward |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | The invention relates to 2-penem-3-carboxylic acid compounds of the formula ##STR1## in which Ra represents an organic radical bonded by a carbon atom to the ring carbon atom, a free, etherified or esterified hydroxy or mercapto group or a halogen atom, R1 represents hydrogen, an organic radical bonded by a carbon atom to the ring carbon atom, or an etherified mercapto group, and R2 represents a hydroxy group or an R2 A radical that together with the carbonyl grouping --C(â•O)-- forms a protected carboxyl group, and to salts of such compounds with salt-forming groups, processes for the manufacture of such compounds, pharmaceutical preparations containing compounds of the formula I with pharmacological properties, and their use. The compounds have antibiotic activity. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 2/79 |
| Publication No: | US 4579684 A |
| Title: | Process for the manufacture of enol derivatives |
| Publication Type: | Grant |
| Publication Date: | Aug 19, 1985 |
| Filing Date: | Feb 20, 1975 |
| Inventors: | Robert B. Woodward, Hans Bickel |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | The invention concerns a process for the manufacture of 7 beta -amino-3-cephem-3-ol-4-carboxylic acid compounds by ring closure of esters of2-[4-(substituted-thio)-3-acylamino-2-xoazetidin-1-yl]-3-substituted-amino-crotonic acids and solvolysing the enamino group in the resulting 7 beta -acylamino-3-substituted-amino-cephem-4-carboxylic acid esters. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 3/79 |
| Publication No: | US 4500457 A |
| Title: | Process for preparing thia-aza compounds with a beta-lactam ring |
| Publication Type: | Grant |
| Publication Date: | Feb 19, 1985 |
| Filing Date: | Mar 1, 1982 |
| Inventors: | Jacques Gosteli, Ivan Ernest, Robert B. Woodward |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | 2-Penem-3-carboxylic acid compounds of the formula (I) in which R1 represents hydrogen, an organic radical bonded by a carbon atom to the ring carbon atom or an etherified mercapto group and R2 represents hydroxy or a radical R2A forming together with the carbonyl grouping -C(=O)- a protected carboxyl group, 1-oxides thereof, as well as salts of such compounds having salt-forming groups, in racemic and optically active form, processes for their preparation, pharmaceutical compositions containing such compounds, and their use as antibiotics, and intermediates and their processes which are useful in the production of the compounds of the formula I. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 4/79 |
| Publication No: | US 4434287 A |
| Title: | Process for the manufacture of enol derivatives |
| Publication Type: | Grant |
| Publication Date: | Oct 29, 1985 |
| Filing Date: | Sep 30, 1982 |
| Inventors: | Robert E. Woodward, Hans Bickel |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | The invention concerns a process for the manufacture of 7 beta -amino-3-cephem-3-ol-4-carboxylic acid compounds by ring closure of esters of 2-[4-(substituted-thio)-3-acylamino-2-oxoazetidin-1-yl]-3-substituted- amino-crotonic acids and solvolyzing the enamino group in the resulting 7 beta -acylamino-3-substituted-amino-cephem-4-carboxylic acid esters. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 5/79 |
| Publication No: | US 4364865 A |
| Title: | Bicyclic unsaturated thia-aza compounds and 4-acylthio azetidinone intermediates |
| Publication Type: | Grant |
| Publication Date: | Dec 21, 1982 |
| Filing Date: | Jun 11, 1980 |
| Inventors: | Ivan Ernest, Jacques Gosteli, Robert B. Woodward |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | The invention relates to 6-amino-2-penem-3-carboxylic acid compounds of the formula ##STR1## in which R1 a denotes hydrogen or an amino protective group R1 A and R1 b represents hydrogen or an acyl radical Ac, or in which R1 a and R1 b conjointly form a bivalent amino protective group, R2 denotes hydroxyl or a radical R2 A which, together with the carbonyl grouping --C(â•O)--, forms a protected carboxyl group, and R3 represents hydrogen or an organic radical which is linked via a carbon atom to the ring carbon atom, and 1-oxides thereof, as well as salts of such compounds having salt-forming groups, which compounds possess antibiotic properties, processes for the manufacture of such compounds, and also pharmaceutical formulations containing compounds of the formula I with pharmacological properties, and the use thereof, either as antibiotics, preferably in the form of pharmaceutical formulations, or as intermediate products. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 6/79 |
| Publication No: | US 4331676 A |
| Title: | Thia-aza compounds with a β-lactam ring |
| Publication Type: | Grant |
| Publication Date: | May 25, 1982 |
| Filing Date: | May 4, 1978 |
| Inventors: | Jacques Gosteli, Ivan Ernest, Robert B. Woodward |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | 2-Penem-3-carboxylic acid compounds of the formula ##STR1## in which R1 represents hydrogen, an organic radical bonded by a carbon atom to the ring carbon atom or an etherified mercapto group and R2 represents hydroxy or a radical R2 A forming together with the carbonyl grouping --C(â•O)-- a protected carboxyl group, 1-oxides thereof, as well as salts of such compounds having salt-forming groups, in racemic and optically active form, processes for their preparation, pharmaceutical compositions containing such compounds, and their use as antibiotics, and intermediates and their processes which are useful in the production of the compounds of the formula I. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 7/79 |
| Publication No: | US 4301278 A |
| Title: | Process for the manufacture of enol derivatives |
| Publication Type: | Grant |
| Publication Date: | Nov 17, 1981 |
| Filing Date: | Mar 26, 1979 |
| Inventors: | Robert B. Woodward, Hans Bickel |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | 7β-Amino-3-cephem-3-cl-4-carboxylic-acid compounds of the formula ##STR1## wherein R1 a represents hydrogen or an amino protective group R1 A and R1 b represents hydrogen or an acyl group Ac, or R1 a and R1 b together represent a bivalent amino protective group, R2 represents hydroxyl or a radical R2 A which together with the carbonyl grouping --C(â•O)-- forms a protected carboxyl group and R3 represents hydrogen, lower alkyl or a hydroxyl protective group, and 1-oxides of 3-cephem compounds of the formula IA, and the corresponding 2-cephem compounds are prepared in that a compound of the formula ##STR2## wherein R1 a, R1 b and R2 A have the meanings mentioned under formula IA, R3 o represents lower alkyl or a hydroxyl protective group and Y represents a group which is removed, is treated with a base; also comprised are intermediate products. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 8/79 |
| Publication No: | US 4256739 A |
| Title: | 7β-Amino-3-thio-3-cephem-4-carboxylic acid compounds, and antibacterial compositions and methods using them |
| Publication Type: | Grant |
| Publication Date: | Mar 17, 1981 |
| Filing Date: | Aug 26, 1975 |
| Inventors: | Robert B. Woodward, Hans Bickel |
| Original Assignee: | Robert B. Woodward, Hans Bickel |
| Abstract: | 7β-Amino-3-R3 -thio-3-cephem-4-carboxylic acid compounds of the formula ##STR1## wherein R1 a represents hydrogen or an amino protective group R1 A and R1 b represents hydrogen or an acyl group Ac, or R1 a and R1 b conjointly represent a divalent amino protective group, R2 represents hydroxyl or a radical R2 A which, conjointly with the carbonyl grouping --C(â•O)--, forms a protected carboxyl group and R3 represents an unsubstituted or substituted hydrocarbon radical or an unsubstituted or substituted heterocyclic radical, and salts of such compounds with salt-forming groups possess antibiotic properties. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 9/79 |
| Publication No: | US 4255328 A |
| Title: | Sulfide intermediates for the manufacture of enol derivatives |
| Publication Type: | Grant |
| Publication Date: | Mar 10, 1981 |
| Filing Date: | Nov 20, 1978 |
| Inventors: | Nov 20, 1978 |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | 7β-amino-3-cephem-3-ol-4-carboxylic-acid compounds of the formula ##STR1## wherein R1 a represents hydrogen or an amino protective group R1 A and R1 b represents hydrogen or an acyl group Ac, or R1 a and R1 b together represent a bivalent amino protective group, R2 represents hydroxyl or a radical R2 A which together with the carbonyl grouping --C(â•O)-- forms a protected carboxyl group and R3 represents hydrogen, lower alkyl or a hydroxyl protective group, and 1-oxides of 3-cephem compounds of the formula IA, and the corresponding 2-cephem compounds are prepared in that a compound of the formula ##STR2## wherein R1 a, R1 b and R2 A have the meanings mentioned under formula IA, R3 o represents lower alkyl or a hydroxyl protective group and Y represents a group which is removed, is treated with a base; also comprised are intermediate products. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 10/79 |
| Publication No: | US 4161476 A |
| Title: | α-Halo-2-oxo-1-azetidinemethane-carboxylic acid compounds |
| Publication Type: | Grant |
| Publication Date: | Jul 17, 1979 |
| Filing Date: | Jul 11, 1977 |
| Inventors: | Karl Heusler, Robert B. Woodward |
| Original Assignee: | Karl Heusler, Robert B. Woodward |
| Abstract: | α-Hydroxy-2-oxo-1-azetidinemethane-carboxylic acid compounds of formula ##STR1## wherein R1 represents a hydrogen atom or the organic residue of an alcohol, R2 represents a hydrogen atom or an acyl residue, R3 represents an organic residue and R4 represents a hydrogen atom, when R2 stands for an acyl residue, or the two groups R3 and R4 together represent a disubstituted carbon atom, when R2 stands for a hydrogen atom or an acyl group, are useful as intermediates for the manufacture of pharmacologically active compounds. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 11/79 |
| Publication No: | US 4147864 A |
| Title: | Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds |
| Publication Type: | Grant |
| Publication Date: | Apr 3, 1979 |
| Filing Date: | Dec 2, 1976 |
| Inventors: | Robert B. Woodward, Hans Bickel |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | 7β-amino-3-cephem-3-ol-4-carboxylic-acid compounds of the formula ##STR1## wherein R1 a represents hydrogen or an amino protective group R1 A and R1 Brepresents hydrogen or an acyl group Ac, or R1 a and R1 b together represent abivalent amino protective group, R2 represents hydroxyl or a radical R2 A which together with the carbonyl grouping --C(â•O)-- forms a protected carboxyl group and R3 represents hydrogen, lower alkyl or a hydroxyl protective group, and 1-oxides or 3-cephem compounds of the formula IA, and the corresponding 2-cephem compounds are prepared in that a compound of the formula ##STR2## wherein R1a, R1 b and R2 A have the meanings mentioned under formula IA, R3 o represents lower alkyl or a hydroxyl protective group and Y represents a group which is removed, is treated with a base; also comprised are intermediate products. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 12/79 |
| Publication No: | US 4110533 A |
| Title: | Process for the manufacture of enol derivatives |
| Publication Type: | Grant |
| Publication Date: | Aug 29, 1978 |
| Filing Date: | Feb 10, 1976 |
| Inventors: | Robert B. Woodward, Hans Bickel |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | The invention concerns a process for the manufacture of 7β-amino-3-cephem-3-ol-4-carboxylic acid compounds by ring closure of esters of 2-[4-(substituted-thio)-3-acylamino-2-oxoazetidin-1-yl]-3-substituted-amino-crotonic acids and solvolysing the enamino group in the resulting 7β-acylamino-3-substituted-amino-cephem-4-carboxylic acid esters. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 13/79 |
| Publication No: | US 4070477 A |
| Title: | 2-Penem compounds |
| Publication Type: | Grant |
| Publication Date: | Jan 24, 1978 |
| Filing Date: | Dec 2, 1976 |
| Inventors: | Ivan Ernest, Jacques Gosteli, Robert Burns Woodward |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | The invention relates to 6-amino-2-penem-3-carboxylic acid compounds of the formula ##STR1## in which R1 a denotes hydrogen or an amino protective group R1 A and R1 b represents hydrogen or an acyl radical Ac, or in which R1 a and R1 b conjointly form a bivalent amino protective group, R2 denotes hydroxyl or aradical R2 A which, together with the carbonyl grouping --C(â•0)--, forms aprotected carboxyl group, and R3 represents hydrogen or an organic radical which is linked via a carbon atom to the ring carbon atom, and 1-oxides thereof, as well as salts of such compounds having salt-forming groups, which compounds possess antibiotic properties, processes for the manufacture of such compounds, and also pharmaceutical formulations containing compounds of the formula I with pharmacological properties, and the use thereof, either as antibiotics, preferably in the form of pharmaceutical formulations, or as intermediate products. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 14/79 |
| Publication No: | US 4052408 A |
| Title: | Oxyacetic acid compounds and process for their manufacture |
| Publication Type: | Grant |
| Publication Date: | Oct 4, 1977 |
| Filing Date: | Nov 18, 1974 |
| Inventors: | Karl Heusler, Robert Burns Woodward |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | α-Hydroxy-2-oxo-1-azetidinemethane-carboxylic acid compounds of formula ##STR1## wherein R1 represents a hydrogen atom or the organic residue of an alcohol, R2 represents a hydrogen atom or an acyl residue, R3 represents an organic residue and R4 represents a hydrogen atom, when R2 stands for an acyl residue, or the two groups R3 and R4 together represent a disubstituted carbon atom, when R2 stands for a hydrogen atom or an acyl group, are useful as intermediates for the manufacture of pharmacologically active compounds. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 15/79 |
| Publication No: | US 3950362 A |
| Title: | Oxabicyclooctanes and process for their manufacture |
| Publication Type: | Grant |
| Publication Date: | Apr 13, 1976 |
| Filing Date: | Feb 2, 1973 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | Compounds of the formula ##SPC1## Wherein Z4Â and Z5Â each independently represent free, etherified or esterified hydroxy groups, are produced by diazotisation of 2-exo-amino-3,4-endo-dihydroxy-8-Z4Â -7-oxabicyclo [4,3,0]nonane followed by ring contraction, they are intermediates in the synthesis of prostaglandins. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 16/79 |
| Publication No: | US 3941813 A |
| Title: | Dioxatricyclodecanes and process for their manufacture |
| Publication Type: | Grant |
| Publication Date: | March 2, 1976 |
| Filing Date: | February 2, 1973 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | A compound of formula IS PRODUCED BY REACTING 4 alpha ,5 alpha -EPOXY-9,10-DIOXATRICYCLO[4,3,1,03,8]DECANE WITH AMMONIA OR A REACTION FUNCTIONAL DERIVATIVE THEREOF; IT IS AN INTERMEDIATE FOR THE SYNTHESIS OF PROSTAGLANDINS. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 17/79 |
| Publication No: | US 3919249 A |
| Title: | Dioxatricyclodecanol, esters thereof, and process for their manufacture |
| Publication Type: | Grant |
| Publication Date: | Nov 11, 1975 |
| Filing Date: | Feb 2, 1973 |
| Inventors: | Robert Burns Woodward |
| Original Assignee: | Ciba Geigy Corp |
| Abstract: | Compounds of formula WHEREIN Z3 represents a free or esterified hydroxy group are prepared by cyclising an ester of 3-hydroxymethyl-2,4-dioxabicyclo[3,3,1 non-6-ene; they are intermediates for the synthesis of prostaglandins |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 18/79 |
| Publication No: | US 3914258 A |
| Title: | New oxabicyclononanes |
| Publication Type: | Grant |
| Publication Date: | Oct 21, 1975 |
| Filing Date: | Feb 2, 1973 |
| Inventors: | Robert Burns Woodward |
| Original Assignee: | Ciba Geigy Corp |
| Abstract: | Compounds of the formula WHEREIN Z4 represents a free, esterified or etherified hydroxy group, are produced by solvolysing 4 beta -amino-9,10-dioxatricyclo [4,3,1,03,8]decan-5 alpha -ol; they are intermediates in the synthesis of prostaglandins. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 19/79 |
| Publication No: | US 3901919 A |
| Title: | Bicyclononane diol and esters |
| Publication Type: | Grant |
| Publication Date: | Aug 26, 1975 |
| Filing Date: | Feb 2, 1973 |
| Inventors: | Robert Burns Woodward |
| Original Assignee: | Ciba Geigy Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 20/79 |
| Publication No: | US 3900500 A |
| Title: | Esters of hydroxymethyl-dioxabicyclononene |
| Publication Type: | Grant |
| Publication Date: | Aug 19, 1975 |
| Filing Date: | Feb 2, 1973 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Ciba Geigy Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 21/79 |
| Publication No: | US 3898248 A |
| Title: | Dioxatricyclodecenes |
| Publication Type: | Grant |
| Publication Date: | Aug 5, 1975 |
| Filing Date: | Feb 2, 1973 |
| Inventors: | Robert Burns Woodward |
| Original Assignee: | Ciba Geigy Corp |
| Abstract: | A compound of the formula IS PREPARED BY ELIMINATING THE ESTER GROUP FROM ONE ESTER OF 9,10-DIOXATRICYCLO[4,3,1,03,8]DECAN-4 beta -OL; IT IS AN INTERMEDIATE FOR THE SYNTHESIS OF PROSTAGLANDINS. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 22/79 |
| Publication No: | US 3880833 A |
| Title: | Certain bis-(3-amino-2-oxo-1-azetidinyl)-disulfides |
| Publication Type: | Grant |
| Publication Date: | Apr 29, 1975 |
| Filing Date: | Oct 12, 1971 |
| Inventors: | Hans Bickel, Karl Heusler, Riccardo Scartazzini, Robert Burns Woodward |
| Original Assignee: | Ciba Geigy Corp |
| Abstract: | The invention concerns the manufacture of bis-(cis-3-amino-2-oxo-1-azetidinyl)-disulfides and corresponding N-protected derivatives thereof by oxidation of 4-thia-2,6-diaza-bicyclo[3.2.0]heptan-6-ones and, if desired, protection, e.g. acylation, of the amino group. The products are intermediates for the manufacture of 7-amino-ceph-3-em-4-carboxylic acid compounds with antibiotic properties. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 23/79 |
| Publication No: | US 3862225 A |
| Title: | D-ring substituted tetracyclines |
| Publication Type: | Grant |
| Publication Date: | Jan 21, 1975 |
| Filing Date: | Jan 7, 1971 |
| Inventors: | Lloyd H Conover, Robert B Woodward |
| Original Assignee: | Pfizer |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 24/79 |
| Publication No: | US 3835130 A |
| Title: | 2-thia-cepham and cephem-4-carboxylic acids |
| Publication Type: | Grant |
| Publication Date: | Sep 10, 1974 |
| Filing Date: | Oct 29, 1971 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Ciba Geigy Corp |
| Abstract: | The invention concerns 7-amino-2-thiacepham-4-carboxylic acid and 7-amino-2-thiaceph-3-em-4-carboxylic acid compounds and their N-acyl derivatives. These compounds, particularly the latter ones have antibacterial properties. The invention also concerns process for the manufacture of such compounds and intermediates and starting materials useful in such process. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 25/79 |
| Publication No: | US 3719672 A |
| Title: | 4-substituted methylene-7-amino-8-oxo-5-thia-1-aza-bicyclo(4,2,0 oct-2-ene-2-carboxylic acids |
| Publication Type: | Grant |
| Publication Date: | Mar 6, 1973 |
| Filing Date: | Dec 2, 1969 |
| Inventors: | I Ernest, K Heusler, R Woodward |
| Original Assignee: | Ciba Geigy Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 26/79 |
| Publication No: | US 3716465 A |
| Title: | Process for the manufacture of thiazacyclic hydroxy compounds |
| Publication Type: | Grant |
| Publication Date: | Feb 13, 1973 |
| Filing Date: | Nov 23, 1970 |
| Inventors: | K Heusler, R Woodward |
| Original Assignee: | Ciba Geigy Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 27/79 |
| Publication No: | US 3697552 A |
| Title: | Anthracyclidine-acetic acid derivatives |
| Publication Type: | Grant |
| Publication Date: | Oct 10, 1972 |
| Filing Date: | Oct 31, 1969 |
| Inventors: | Lloyd H Conover, Robert B Woodward |
| Original Assignee: | Pfizer |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 28/79 |
| Publication No: | US 3681370 A |
| Title: | Certain acyloxy thiazolidines and process for their manufacture |
| Publication Type: | Grant |
| Publication Date: | Aug 1, 1972 |
| Filing Date: | Nov 24, 1969 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Woodward, Robert B. |
| Abstract: | Process which comprises treating a saturated cyclic alpha -hydrazino-thioether, in which the hydrazino group is N,N'-disubstituted by esterified carboxyl groups, with an oxidation reagent capable of furnishing an acyloxy group; in a resulting saturated cyclic alpha -acyloxy-thioether the acyloxy group may be converted into the hydroxyl group. The products are useful in the synthesis of 7-amino-cephalosporanic acids. |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 29/79 |
| Publication No: | US 3509184 A |
| Title: | Anthracyclidine-acetic acid derivatives |
| Publication Type: | Grant |
| Publication Date: | Apr 28, 1970 |
| Filing Date: | Aug 1, 1966 |
| Inventors: | Lloyd H Conover, Robert B Woodward |
| Original Assignee: | Pfizer & Co C |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 30/79 |
| Publication No: | US 3502697 A |
| Title: | Antibacterial agents |
| Publication Type: | Grant |
| Publication Date: | Mar 24, 1970 |
| Filing Date: | Jan 3, 1967 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Pfizer & Co C |
| Abstract: | No Abstract |
| Title: | |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 31/79 |
| Publication No: | US 3502660 A |
| Title: | 2-((5'-(3' and/or 4'-substituted)isoxazoyl) methylidene)-3,4,10-trioxo-1,2,3,4,4a,9,9a,10-octahydroanthracenes |
| Publication Type: | Grant |
| Publication Date: | Mar 24, 1970 |
| Filing Date: | Jan 12, 1967 |
| Inventors: | Kenneth Butler, Lloyd H Conover, Robert B Woodward |
| Original Assignee: | Pfizer & Co C |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 32/79 |
| Publication No: | US 3498996 A |
| Title: | Process for manufacture of 5-esterified hydroxy - thiazolidine - 4 - carboxylic acids |
| Publication Type: | Grant |
| Publication Date: | Mar 3, 1970 |
| Filing Date: | Jan 26, 1967 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Woodward, Robert B. |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 33/79 |
| Publication No: | US 3497532 A |
| Title: | Antibacterial agents |
| Publication Type: | Grant |
| Publication Date: | Feb 24, 1970 |
| Filing Date: | Sep 2, 1966 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Pfizer & Co C |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 34/79 |
| Publication No: | US 3483216 A |
| Title: | 2,2-disubstituted 3-acyl-5-amino-thiazolidine-4-carboxylic acids |
| Publication Type: | Grant |
| Publication Date: | Dec 9, 1969 |
| Filing Date: | Aug 22, 1966 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Woodward, Robert B. |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 35/79 |
| Publication No: | US 3468933 A |
| Title: | Hydroxymethane carboxylic acid esters and process for their manufacture |
| Publication Type: | Grant |
| Publication Date: | Sep 23, 1969 |
| Filing Date: | Aug 22, 1966 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Woodward, Robert B. |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 36/79 |
| Publication No: | US 3449336 A |
| Title: | Process for preparing novel intermediates useful for preparing 7-amino-cephalosporanic acid and derivatives thereof |
| Publication Type: | Grant |
| Publication Date: | Jun 10, 1969 |
| Filing Date: | Aug 22, 1966 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Woodward, Robert B. |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 37/79 |
| Publication No: | US 3329670 A |
| Title: | Arylazopyrazole lactone dyes |
| Publication Type: | Grant |
| Publication Date: | Jul 4, 1967 |
| Filing Date: | Feb 3, 1966 |
| Inventors: | Dershowitz Samuel, Robert B Woodward |
| Original Assignee: | Polaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 38/79 |
| Publication No: | US 3288778 A |
| Title: | Azo and anthraquinone dye developers |
| Publication Type: | Grant |
| Publication Date: | Nov 29, 1966 |
| Filing Date: | Oct 5, 1964 |
| Inventors: | Blout Elkan R, Cohen Saul G, Rogers Howard G, Simon Myron S, Woodward Robert B |
| Original Assignee: | Polaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 39/79 |
| Publication No: | US 3252969 A |
| Title: | p-dihydroxyphenyl sulfamyl azo and anthraquinone dyestuffs |
| Publication Type: | Grant |
| Publication Date: | May 24, 1966 |
| Filing Date: | Nov 7, 1962 |
| Inventors: | Blout Elkan R, Milton Green, Rogers Howard G, Woodward Robert B |
| Original Assignee: | Polaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 40/79 |
| Publication No: | US 3249643 A |
| Title: | Tricyclo [5. 2. 1. 04, 10]-2, 5, 8-decatriene |
| Publication Type: | Grant |
| Publication Date: | May 3, 1966 |
| Filing Date: | Jan 7, 1964 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Woodward, Robert B. |
| Abstract: | No Ahstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 41/79 |
| Publication No: | US 3230085 A |
| Title: | Photographic products, processes and compositions |
| Publication Type: | Grant |
| Publication Date: | Jan 18, 1966 |
| Filing Date: | Apr 6, 1961 |
| Inventors: | Samuel Dershowitz, Woodward Robert B |
| Original Assignee: | Polaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 42/79 |
| Publication No: | US 3209016 A |
| Title: | Anthraquinone derivatives containing an ortho- or para-dihydroxyphenylalkylamino substituent |
| Publication Type: | Grant |
| Publication Date: | Sep 28, 1965 |
| Filing Date: | Oct 25, 1963 |
| Inventors: | Blout Elkan R, Cohler Marilyn R, Milton Green, Simon Myron S, Woodward Robert B |
| Original Assignee: | Polaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 43/79 |
| Publication No: | US 3188348 A |
| Title: | 12alpha-deoxytetracycline oxidation process |
| Publication Type: | Grant |
| Publication Date: | Jun 8, 1965 |
| Filing Date: | Jul 9, 1962 |
| Inventors: | Philip N Gordon, Butler Kenneth, Robert B Woodward |
| Original Assignee: | Pfizer & Co C |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 44/79 |
| Publication No: | US 3135606 A |
| Title: | Novel photographic products and processes employing anthraquinone dye |
| Publication Type: | Grant |
| Publication Date: | Jun 2, 1964 |
| Filing Date: | Oct 26, 1962 |
| Inventors: | Blout Elkan R, Cohler Marilyn R, Milton Green, Simon Myron S, Woodward Robert B |
| Original Assignee: | Polaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 45/79 |
| Publication No: | US 3019107 A |
| Title: | Novel photographic products, processes and compositions |
| Publication Type: | Grant |
| Publication Date: | Jan 30, 1962 |
| Filing Date: | Sep 25, 1956 |
| Inventors: | Elkan R Blout, Howard G Rogers, Myron S Simon, Robert B Woodward |
| Original Assignee: | Polaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 46/79 |
| Publication No: | US 2883384 A |
| Title: | Production of reserpine and analogs thereof |
| Publication Type: | Grant |
| Publication Date: | April 21, 1959 |
| Filing Date: | May 3, 1956 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Research Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 47/79 |
| Publication No: | US 2857275 A |
| Title: | Photographic compositions and processes |
| Publication Type: | Grant |
| Publication Date: | Oct 21, 1958 |
| Filing Date: | Nov 8, 1954 |
| Inventors: | Blout Elkan R, Cohen Saul G, Land Edwin H, Milton Green, Tracy Helen J, Woodward Robert B |
| Original Assignee: | Polaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 48/79 |
| Publication No: | US 2857274 A |
| Title: | Photographic compositions and processes |
| Publication Type: | Grant |
| Publication Date: | Oct 21, 19584 |
| Filing Date: | Sep 4, 1953 |
| Inventors: | Blout Elkan R, Cohen Saul G, Land Edwin H, Milton Green, Tracy Helen J, Woodward Robert B |
| Original Assignee: | GPolaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 49/79 |
| Publication No: | US 2802873 A |
| Title: | Production of steroid intermediate |
| Publication Type: | Grant |
| Publication Date: | Aug 13, 1957 |
| Filing Date: | Apr 13, 1951 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Research Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 50/79 |
| Publication No: | US 2745879 A |
| Title: | Hexahydronaphthalenes and production thereof |
| Publication Type: | Grant |
| Publication Date: | May 15, 1956 |
| Filing Date: | May 19, 1953 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Research Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 51/79 |
| Publication No: | US 2702805 A |
| Title: | Production of steroids |
| Publication Type: | Grant |
| Publication Date: | Feb 22, 1955 |
| Filing Date: | May 19, 1953 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Research Corp |
| Abstract: | No Absract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 52/79 |
| Publication No: | US 2701807 A |
| Title: | Steroid aldehydes and process |
| Publication Type: | Grant |
| Publication Date: | Feb 8, 1955 |
| Filing Date: | Jan 31, 1952 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Research Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 53/79 |
| Publication No: | US 2687435 A |
| Title: | 1, 14-dimethyl-2-keto-6, 7-dihydroxy-2, 3, 4, 5, 6, 7, 8, 12, 13, 14-decahydrophenan-threne and process for preparing same |
| Publication Type: | Grant |
| Publication Date: | Aug 24, 1954 |
| Filing Date: | May 19, 1953 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Research Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 54/79 |
| Publication No: | US 2681366 A |
| Title: | Production of 2-keto-10-methyl-1, 2, 5, 8, 9, 10-hexahydronaphthalene |
| Publication Type: | Grant |
| Publication Date: | Jun 15, 1954 |
| Filing Date: | Jan 31, 1952 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Research Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 55/79 |
| Publication No: | US 2675396 A |
| Title: | Steroid aldehydes and process |
| Publication Type: | Grant |
| Publication Date: | Apr 13, 1954 |
| Filing Date: | May 19, 1953 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Woodward, Robert B. |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 56/79 |
| Publication No: | US 2674533 A |
| Title: | Compositions and processes for the development of silver halide elements |
| Publication Type: | Grant |
| Publication Date: | Apr 6, 1954 |
| Filing Date: | Jul 10, 1952 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Polaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 57/79 |
| Publication No: | US 2672482 A |
| Title: | AProduction of steroids |
| Publication Type: | Grant |
| Publication Date: | Mar 16, 1954 |
| Filing Date: | Jan 31, 1952 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Research Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 58/79 |
| Publication No: | US 2657972 A |
| Title: | Copolymer of l-leucine and dl-phenylalanine |
| Publication Type: | Grant |
| Publication Date: | Nov 3, 1953 |
| Filing Date: | Sep 6, 1952 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Woodward, Robert B. |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 59/79 |
| Publication No: | US 2520673 A |
| Title: | Acid salts of an n-acetyl-10-trimethylammoniumdihydrohomomeroquinene ethyl ester and their production |
| Publication Type: | Grant |
| Publication Date: | Aug 29, 1950 |
| Filing Date: | Mar 22, 1949 |
| Inventors: | Doering William Von Eggers, Robert B Woodward |
| Original Assignee: | Polaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 60/79 |
| Publication No: | US 2494689 A |
| Title: | Method and apparatus for producing twisted thermoplastic resin strips |
| Publication Type: | Grant |
| Publication Date: | Jan 17, 1950 |
| Filing Date: | Feb 25, 1947 |
| Inventors: | Robert W Canfield, Robert B Woodward |
| Original Assignee: | Plax Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 61/79 |
| Publication No: | US 2475932 A |
| Title: | 7-hydroxyisoquinoline derivatives and methods of preparing the same |
| Publication Type: | Grant |
| Publication Date: | Jul 12, 1949 |
| Filing Date: | Nov 4, 1943 |
| Inventors: | Doering William Von Eggers, Robert B Woodward |
| Original Assignee: | Polaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 62/79 |
| Publication No: | US 2447831 A |
| Title: | Evaporated and deposited birefringent film comprising aromatic compound, the molecules of which contain planar groupings |
| Publication Type: | Grant |
| Publication Date: | Aug 24, 1948 |
| Filing Date: | Mar 3, 1945 |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Polaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 63/79 |
| Publication No: | US 2441019 A |
| Title: | Light-polarizing suspension of oriented crystals of dibenzacridine periodide in cellulose acetate |
| Publication Type: | Grant |
| Publication Date: | May 4, 1948 |
| Filing Date: | Dec 16, 1943 |
| Inventors: | Jr William F Amon, Edwin H Land, Gofstein Raiph, Georgian Vlasios, Cutler D West, Robert B Woodward |
| Original Assignee: | Polaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 64/79 |
| Publication No: | US 2395526 A |
| Title: | Isoquinoline derivatives and methods of preparing the same |
| Publication Type: | Grant |
| Publication Date: | Feb 26, 1946 |
| Filing Date: | Feb 25, 1944 |
| Inventors: | Doering William Von Eggers, Robert B Woodward |
| Original Assignee: | Polaroid Corp |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 65/79 |
| Publication No: | JP 01110668 A |
| Title: | No Title |
| Publication Type: | No Publication Type |
| Publication Date: | No Publication Date |
| Filing Date: | No Filing Date |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | No Original Assignee |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 66/79 |
| Publication No: | CH 627759 A |
| Title: | Process for preparing enol ether compounds |
| Publication Type: | Grant |
| Publication Date: | Jan 29, 1982 |
| Filing Date: | No Filing Date |
| Inventors: | Woodward, Robert B., Bickel Hans |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | The invention provides a novel process for preparing O-substituted7beta-amino-3-cephem-3-ol-4-carboxylic acid compounds of the formula where R1 {a} is hydrogen or an amino-protective group R1{A}, R1 is hydrogen or an acyl group Ac, or R1{a} and R1 together are a bivalent amino-protective group, R2 is hydroxyl or a radical R2{A} which, together with the carbonyl group -C(=O)-, forms a protected carboxyl group, and R3 is lower alkyl or optionally substituted alpha -phenyl (lower alkyl), which comprises etherifying the 3-hydroxyl group in a 3-cephem-3-ol compound |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 67/79 |
| Publication No: | CH 621337 A |
| Title: | Process for the preparation of 3-aminocrotonylazetidinone derivatives |
| Publication Type: | Grant |
| Publication Date: | Jan 30, 1981 |
| Filing Date: | No Filing Date |
| Inventors: | Woodward Robert Burns, Bickel Hans |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 68/79 |
| Publication No: | CH 620444 A |
| Title: | Process for the preparation of bicyclic unsaturated thiaaza compounds |
| Publication Type: | Grant |
| Publication Date: | Nov 28, 1980 |
| Filing Date: | No Filing Date |
| Inventors: | Woodward, Robert B., Ernest Ivan |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 69/79 |
| Publication No: | CH 619232 A |
| Title: | Process for the preparation of substituted 3-cephem- or 2-cephem-3-mercapto-4-carboxylic acids |
| Publication Type: | Grant |
| Publication Date: | Sep 15, 1980 |
| Filing Date: | No Filing Date |
| Inventors: | Woodward, Robert B., Bickel Hans |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | No Abstract |
| Title: | |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 70/79 |
| Publication No: | CH 614959 A |
| Title: | Process for the preparation of 7-beta-aminocephem-3-01-4-carboxylic acid compounds |
| Publication Type: | Grant |
| Publication Date: | Dec 28, 1979 |
| Filing Date: | No Filing Date |
| Inventors: | Woodward, Robert B. |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 71/79 |
| Publication No: | CH 612422 A |
| Title: | Process for the preparation of etherified 2-azetidinyl-3-hydroxycrotonic acid derivatives |
| Publication Type: | Grant |
| Publication Date: | Jul 31, 1979 |
| Filing Date: | No Filing Date |
| Inventors: | Woodward, Robert B., Bickel Hans |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 72/79 |
| Publication No: | CH 610584 A |
| Title: | Process for the preparation of 2-(3-amino-2-oxo-4-sulphonylthio-1- azetidinyl)-3-methylenebutyric acid derivatives |
| Publication Type: | Grant |
| Publication Date: | Apr 30, 1979 |
| Filing Date: | No Filing Date |
| Inventors: | Woodward, Robert B., Bickel Hans |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 73/79 |
| Publication No: | CH 605999 A |
| Title: | 3-Thio-7-amino-3- and-2-cephem-4-carboxylic acids |
| Publication Type: | Grant |
| Publication Date: | Oct 13, 1978 |
| Filing Date: | No Filing Date |
| Inventors: | Woodward, Robert B., Bickel Hans |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | No Abstract |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 74/79 |
| Publication No: | CH 605998 A |
| Title: | 3-Thio-7-amino-3- and-2-cephem-4-carboxylic acids |
| Publication Type: | Grant |
| Publication Date: | Oct 13, 1978 |
| Filing Date: | No Filing Date |
| Inventors: | Woodward, Robert B., Bickel Hans |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | 3-Thio-7-amino-3- and-2-cephem-4-carboxylic acids useful as broad-spectrum antibacterials and inters(NL-2.3.76)t |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 75/79 |
| Publication No: | CH 605737 A |
| Title: | 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn |
| Publication Type: | Grant |
| Publication Date: | Oct 13, 1978 |
| Filing Date: | DNo Filing Date |
| Inventors: | Woodward, Robert B., Bickel Hans |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn by cyclizing 3-alkoxy-2-(2-oxo-3-amino-4-thio-1-azetidinyl)-crotonic acid derives |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 76/79 |
| Publication No: | CH 602635 A |
| Title: | 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn |
| Publication Type: | Grant |
| Publication Date: | Jul 31, 1978 |
| Filing Date: | No Filing Date |
| Inventors: | Woodward, Robert B., Bickel Hans |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn by cyclizing 3-alkoxy-2-(2-oxo-3-amino-4-thio-1-azetidinyl)-crotonic acid derives |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 77/79 |
| Publication No: | CH 602634 A |
| Title: | 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn |
| Publication Type: | Grant |
| Publication Date: | Jul 31, 1978 |
| Filing Date: | No Filing Date |
| Inventors: | Woodward, Robert B., Bickel Hans |
| Original Assignee: | iba-Geigy Corporation |
| Abstract: | 7-Amino-3-hydroxy-2(or3)-cephem-4-carboxylic acid derivs prepn by cyclizing 3-alkoxy-2-(2-oxo-3-amino-4-thio-1-azetidinyl)-crotonic acid derivs |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 78/79 |
| Publication No: | CH 601310 A |
| Title: | 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn |
| Publication Type: | Grant |
| Publication Date: | Jul 14, 1978 |
| Filing Date: | No Filing Date |
| Inventors: | Woodward, Robert B., Bickel Hans |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | 7-Amino-3-hydroxy-2(or3)-cephem-4-carboxylic acid derivs prepn by cyclizing 3-alkoxy-2-(2-oxo-3-amino-4-thio-1-azetidinyl)-crotonic acid derivs |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
| Publication: | 79/79 |
| Publication No: | CH 601224 A |
| Title: | 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn |
| Publication Type: | Grant |
| Publication Date: | Jun 30, 1978 |
| Filing Date: | No Filing Date |
| Inventors: | Woodward, Robert B., Bickel Hans |
| Original Assignee: | Ciba-Geigy Corporation |
| Abstract: | 7-Amino-3-hydroxy-2(or3)-cephem-4-carboxylic acid derivs prepn by cyclizing 3-alkoxy-2-(2-oxo-3-amino-4-thio-1-azetidinyl)-crotonic acid derivs |
| Representative Figure: | No Figure |
| Family | |
| Details | Google Patents Espacenet |
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Photo Wikipedia Painting Tim Tompkins - PaintHistory.com
Name: Robert Burns Woodward
Birth: 10 April 1917, Boston, MA, USA
Death: 8 July 1979, Cambridge, MA, USA
Institution: Harvard University, Cambridge, MA, USA
Award: "for his outstanding achievements in the art of organic synthesis"
Subject: natural products chemistry, organic chemistry
Portion of Cash: 1/1
Biography
Patents
