®
speaker
Nobel & Laureates Library Online!

Great • Alfred • Nobel • Gives • Aspiration
History of Discovery

Edward Calvin Kendall Ph.D.

The Nobel Prize in Physiology or Medicine 1950
Nobel Co-recipients Tadeus Reichstein, Phillip S.Hench

Chemist. Adrenal cortex hormones including cortisone: structure, biological effects. Thyroid hormone thyroxine: isolated. Glutathione: crystallized, established structure.

What physiologic processes are modified by cortisone and how this influence is exerted are matters still locked within this hormone. Said Shakespeare's soothsayer, "In Nature's infinite book of secrecy a little I can read."

History of Discovery

Excerpt from Nobel Lecture, December 11, 1950

"To chemists, physiologists, and clinicians the results have brought assurance and stimulation. For many patients hope has displaced despair. Progress in the manufacture of cortisone can be illustrated by its price. In July, 1949 the price per gram was $200.00 and this continued until after January, 1950. Since that time the price has been reduced five times: to $150.00, $135.00, $95.00, $50.00, and on November 1, 1950, to $35.00. Furthermore, in 1949 the supply of cortisone was allocated by a committee appointed by the National Academy of Sciences, but today it is available to every physician in the United States."

Title:
The Quest for Cortisone
Author:
Thom Rooke
Publisher:
MSU Press, 2012
ISBN:
1609173260, 9781609173265
Length:
192 pages
Subjects:
Science Life Sciences Biology

Summary: In 1948, when "Mrs. G.," hospitalized with debilitating rheumatoid arthritis, became the first person to receive a mysterious new compound-cortisone-her physicians were awestruck by her transformation from enervated to energized. After eighteen years of biochemical research, the most intensively hunted biological agent of all time had finally been isolated, identified, synthesized, and put to the test. And it worked. But the discovery of a long-sought "magic bullet" came at an unanticipated cost in the form of strange side effects. This fascinating history recounts the discovery of cortisone and pulls the curtain back on the peculiar cast of characters responsible for its advent, including two enigmatic scientists, Edward Kendall and Philip Hench, who went on to receive the Nobel Prize. The book also explores the key role the Mayo Clinic played in fostering cortisone's development, and looks at drugs that owe their heritage to the so-called "King of Steroids."

Title:
Cortisone
Scribners Scientific Memiors
Author:
Edward Calvin Kendall
Publisher:
Scribner, 1071
Length:
175 pages
Subjects:
Science Life Sciences Biochemistry
Title:
ACTH and Cortisone,a New Era in Medicine: An NBC Radio Discussion: Including the Story of Compound E
Author:
John Symonds, Lyon Browne, Edward Calvin Kendall, Alan Titsworth Kenyon
Publisher:
University of Chicago, 1049
Length:
16 pages

Discover Your Abilities and Aspirations!

$10 $25 $50 $100 Other
Tax Exempt 501(c)3 Non-Profit Organization
Any Currency

“One comes to be of just such stuff as that on which the mind is set” - Maithri Upanishath, VI.34:3

“…the peace that is found in libraries and laboratories…” - Louis Pasteur
Copyright © 2017 Ganga Library Inc.   All Rights reserved.   E-Mail: info@gangalib.org
Contact Us
Kendall
Drawing:Newton Llorente

Name: Edward Calvin Kendall
Birth: 8 March 1886, South Norwalk, CT, USA
Death: 4 May 1972, Princeton, NJ, USA
Affiliation at the time of the award: Mayo Clinic, Rochester, MN, USA
Prize motivation: ""for their discoveries relating to the hormones of the adrenal cortex, their structure and biological effects"
Field Biochemistry, endocrinology
Prize share: 1/3
Biography
Books
Goal
History of Discovery
Honoring Edward C. Kendall
Patents
Publications