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Defining Moment
Heck
Photo: Holger Motzkau/Wikimedia Commons

Richard F. Heck Ph.D.

Nobel Prize in Chemistry 2010
Nobel co-recipients Ei-ichi Negishizz, Akira Suzuki

Physical organic chemist. Palladium-catalyzed cross-coupling reaction. Sole author - 7 consecutive papers. Heck reaction: important concept, tool for organic and medicinal chemists; fuorescence labeling of DNA bases - sequencing DNA/Genome. Thinner computer screens in future. "Great art in test tube."

Growing orchids in early teens lead to passion for chemistry.

Defining Moment

Cerf
Photo Courtesy Vinton Cerf. Painting Tim Tompkins - PaintHistory.com

Vinton Cerf Ph.D.

National Medal of Technology and Innovation 1997

One of two Fathers of the Internet. TCP/IP protocols. Internet Architecture. Chief Internet Evangelist, Google. Interplanetary Internet. Living Legend.

"Brilliant, indescribably enthusiastic, humorous, happy, treats people extremely well. It would be nice to go to work every day and work with people like Vint Cerf." – R.V. Nagaveni, Founder, Ganga Library.

Defining Moment

Elion
Photo: Wikimedia Commons

Gertrude B. Elion M.S.[Chemistry]

The Nobel Prize in Physiology or Medicine 1988
Co-Nobelists: Sir James W. Black, George H. Hitchings
National Medal of Science - Chemistry 1991

Chemist, Pharmacologist. Discovered principles for drug treatment; developed drugs - anticancer, immunosuppressive, antiviral, antibacterial, anti-gout, anti-malarial. Purines.

"I was a child with an insatiable thirst for knowledge. My beloved grandfather died of cancer when I was 15. I was highly motivated to discover a cure for this terrible disease".

Defining Moment

Hitchiing

Photo Wikipedia. Painting Tim Tompkins - PaintHistory.com

George H. Hitchings

The Nobel Prize in Physiology or Medicine 1988
Co Nobelists Sir James W. Black, Gertrude B. Elion

Chemist, Pharmacologist. Discovered principles for drug treatment; developed drugs - anticancer, immunosuppressive, antiviral, antibacterial, anti-gout, anti-malarial. Purines. 6-mercaptopurine, Imuran, allopurinol, pyramethamine, trimethoprim, Acyclovir.

“My greatest satisfaction … save lives, relieve suffering. At baptism, my father dedicated my life to service of mankind. Very proud … able to fulfill his hopes.”

Defining Moment

Benzer
Photo: Wiki

Seymour Benzer Ph.D.[Physics]

National Medal of Science - Biological Sciences 1982

Physicist, molecular biologist, behavioral biologist (neurogeneticist). Post Pearl Harbor worked in secret wartime project studying semiconducting properties of germanium, work that foreshadowed development of transistor. Functional gene is a linear stretch of DNA with definable boundaries. Stretches of DNA are all linked to each other as adjacent pieces of chromosome.

Defining Moment

Herbert Brown
Photo Purdue University. Painting Tim Tompkins PaintHistory.com

Herbert C Brown Ph.D.

The Nobel Prize in Chemistry 1979
The President's National Medel of Sciences - Physical Sciences, 1969

Nobel co-recipient Georg Wittig

Organic Chemist. Development of use of boron into important reagents in organic synthesis. School, advanced several times, graduating at 12; refused further advancement, avoiding being sister's classmate.

Graduating, Depression years, future wife Sarah gave him gift, Stock's 'Hydrides of Boron and Silicon' because cheapest chemistry book! Led to Nobel Prize!

Humor/Defining Moment

Nathans
Painting Tim Tompkins PaintHistory.com

Daniel M. Nathans M.D.

The Nobel Prize in Physiology or Medicine 1978
Nobel co-recipients Werner Arber, Hamilton O. Smith
National Medal of Science - Biological Sciences 1993

Physician, Molecular Biologist - Genetics. Restriction enzymes and their application to molecular genetics. Groundwork for human genome project, drug insulin. Able administrator - high signal-to-noise ratio.

"Valuable internship year in medicine with masterful clinician Robert Loeb; The glimpses of human strength and frailty that a physician sees are still with me."

Defining Moments

Nathans
Painting Tim Tompkins - PaintHistory.org

Fritz A. Lipmann M.D.,Ph.D.

The Nobel Prize in Physiology or Medicine 1953
Co-Nobelist Hans Krebs
National Medal of Science - Biological Sciences 1966

Physician, Biochemist. Discovered co-enzyme A, its importance for intermediary metabolism. Identified serine phosphate as constituent of phosphoproteins which contain phosphate. CMP represents metabolically active carbamyl donor.

Liljestrand, Science Academy: …Regarding fundamental discoveries laymen ask for immediate practical application. Counter question of Benjamin Franklin: Of what use is a new-born baby?

Defining Moments

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