Physical organic chemist. Palladium-catalyzed cross-coupling reaction. Sole author - 7 consecutive papers. Heck reaction: important concept, tool for organic and medicinal chemists; fuorescence labeling of DNA bases - sequencing DNA/Genome. Thinner computer screens in future. "Great art in test tube."
Growing orchids in early teens lead to passion for chemistry.
National Medal of Technology and Innovation 1997
One of two Fathers of the Internet. TCP/IP protocols. Internet
Architecture. Chief Internet Evangelist, Google. Interplanetary Internet.
"Brilliant, indescribably enthusiastic, humorous, happy, treats people extremely well. It would be nice to go to work every day and work with people like Vint Cerf." – R.V. Nagaveni, Founder, Ganga Library.
Chemist, Pharmacologist. Discovered principles for drug treatment; developed drugs - anticancer, immunosuppressive, antiviral, antibacterial, anti-gout, anti-malarial. Purines.
"I was a child with an insatiable thirst for knowledge. My beloved grandfather died of cancer when I was 15. I was highly motivated to discover a cure for this terrible disease".
The Nobel Prize in Physiology or Medicine 1988
Co Nobelists Sir James W. Black, Gertrude B. Elion
Chemist, Pharmacologist. Discovered principles for drug treatment; developed drugs - anticancer, immunosuppressive, antiviral, antibacterial, anti-gout, anti-malarial. Purines. 6-mercaptopurine, Imuran,
allopurinol, pyramethamine, trimethoprim, Acyclovir.
“My greatest satisfaction … save lives, relieve suffering. At baptism, my father dedicated my life to service of mankind. Very proud … able to fulfill his hopes.”
National Medal of Science - Biological Sciences 1982
Physicist, molecular biologist, behavioral biologist (neurogeneticist). Post Pearl Harbor worked in secret wartime project studying semiconducting properties of germanium, work that foreshadowed development of transistor. Functional gene is a linear stretch of DNA with definable boundaries. Stretches of DNA are all linked to each other as adjacent pieces of chromosome.
Organic Chemist. Development of use of boron into important reagents in organic synthesis. School, advanced several times, graduating at 12; refused further advancement, avoiding being sister's classmate.
Graduating, Depression years, future wife Sarah gave him gift, Stock's 'Hydrides of Boron and Silicon' because cheapest chemistry book! Led to Nobel Prize!
The Nobel Prize in Physiology or Medicine 1978
Nobel co-recipients Werner Arber, Hamilton O. Smith
National Medal of Science - Biological Sciences 1993
Physician, Molecular Biologist - Genetics. Restriction enzymes and their application to molecular genetics. Groundwork for human genome project, drug insulin. Able administrator - high signal-to-noise ratio.
"Valuable internship year in medicine with masterful clinician Robert Loeb; The glimpses of human strength and frailty that a physician sees are still with me."
The Nobel Prize in Physiology or Medicine 1953
Co-Nobelist Hans Krebs
National Medal of Science - Biological Sciences 1966
Physician, Biochemist. Discovered co-enzyme A, its importance for intermediary metabolism. Identified serine phosphate as constituent of phosphoproteins which contain phosphate. CMP represents metabolically active carbamyl donor.
Liljestrand, Science Academy: …Regarding fundamental discoveries laymen ask for immediate practical application. Counter question of Benjamin Franklin: Of what use is a new-born baby?
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